Literature summary extracted from
Connolly, K.; Rife, J.P.; Culver, G.
Mechanistic insight into the ribosome biogenesis functions of the ancient protein KsgA (2008), Mol. Microbiol., 70, 1062-1075.
Application
EC Number |
Application |
Comment |
Organism |
---|
2.1.1.182 |
medicine |
KsgA as a possible anti-microbial drug target |
Escherichia coli |
Cloned(Commentary)
EC Number |
Cloned (Comment) |
Organism |
---|
2.1.1.182 |
- |
Escherichia coli |
Protein Variants
EC Number |
Protein Variants |
Comment |
Organism |
---|
2.1.1.182 |
E66A |
catalytically inactive enzyme form |
Escherichia coli |
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
---|
2.1.1.182 |
Escherichia coli |
P06992 |
- |
- |
Synonyms
EC Number |
Synonyms |
Comment |
Organism |
---|
2.1.1.182 |
KsgA |
- |
Escherichia coli |
General Information
EC Number |
General Information |
Comment |
Organism |
---|
2.1.1.182 |
malfunction |
cold sensitivity and altered ribosomal profiles are associated with a DELTAksgA genotype in Escherichia coli |
Escherichia coli |
2.1.1.182 |
physiological function |
KsgA acts as a ribosome biogenesis factor. KsgA alters 16S rRNA processing and has a critical role is as a supervisor of biogenesis of 30S subunits in vivo |
Escherichia coli |